當(dāng)前位置:首頁(yè) > 產(chǎn)品中心 > 抗體/抗原 > 一抗 > bsm-63168R磷酸化原癌基因c-Jun重組兔單抗
簡(jiǎn)要描述:C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutatio
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