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  • bs-11440R-BF647BF647標(biāo)記的甲狀腺激素受體β抗體

    Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the biological activities of thyroid hormone (T3). Thyroid hormone receptor b2 (TRb2) is a high affinity receptor for triiodothyronine which belongs to the nuclear hormone receptor family and the NR1 subfamily. It is composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain. Defects in the receptor result in generalized thyroid hormone resistanc

    更新時間:2025-03-09
    型號:bs-11440R-BF647
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:32
  • bs-2101R-BF647BF647標(biāo)記的內(nèi)涎蛋白/內(nèi)皮唾液酸蛋白抗體

    The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.

    更新時間:2025-03-09
    型號:bs-2101R-BF647
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:36
  • bs-6687R-BF488BF488標(biāo)記的鈉離子通道β1抗體

    Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.$nTissue specificity; $n Abundantly expressed in skeletal muscle, heart and brain.

    更新時間:2025-03-09
    型號:bs-6687R-BF488
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:38
  • bs-6670R-BF488BF488標(biāo)記的胰島素樣生長因子2受體抗體

    Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

    更新時間:2025-03-09
    型號:bs-6670R-BF488
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:38
  • bs-6316R-BF647BF647標(biāo)記的前列腺素EP1受體抗體

    PTGER1 is a subtype 1 receptor for prostaglandin E2 (PGE2). This receptor is coupled to the phosphatidylinositol-calcium second messenger system by G(q) proteins. PTGER1 may be an important modulator of renal function and is implicated in the smooth muscle contractile response to PGE2 in various tissues.

    更新時間:2025-03-09
    型號:bs-6316R-BF647
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:33
  • bs-1544R-FITCFITC標(biāo)記的Shh信號轉(zhuǎn)導(dǎo)通路膜蛋白受體抗體

    SHH binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of

    更新時間:2025-03-09
    型號:bs-1544R-FITC
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:36
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